Yes, they're standard VS designer commands available on the main VS menu. You'll see a Format menu appear when you have alignable combinations of top-level shapes selected. We don't currently support aligning to role boxes (the DSL designer has shapes, subshapes, and shapesubfields. Each role box is a shapesubfield), but it's on the list.
The most commonly used commands are Alt-O-A-C (align centers, used to vertically align) and Alt-O-A-M (align middles, used to horizontally align). Aligning Top/Left/Bottom/Right is also supported.
The reference shape (the one that is aligned to) is the primary shape selection, which is discussed in my previous post.